Molecular mechanisms of neuropathological changes in Alzheimer’s disease: a review
نویسندگان
چکیده
منابع مشابه
Molecular mechanisms of neuropathological changes in Alzheimer's disease: a review.
More than 100 years after description of Alzheimer's disease (AD), two major pathological processes observed already by Alois Alzheimer, remain as the main explanation of the pathogenesis of Alzheimer's disease. Important molecular interactions leading to AD neuropathology were described in amyloid cascade and in tau protein function. No clinical trials with novel therapies based on amyloid cas...
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Background: Alzheimer’s disease (AD) is a neurodegenerative disorder with progressive loss of cognitive abilities and memory loss. The aim of this study was to compare neuropathological changes in hippocampus and brain cortex in a rat model of AD. Methods: Adult male Albino Wistar rats (weighing 250-300 g) were used for behavioral and histopathological studies. The rats were randomly assigned t...
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Many people are trying to be smarter every day. How's about you? There are many ways to evoke this case you can find knowledge and lesson everywhere you want. However, it will involve you to get what call as the preferred thing. When you need this kind of sources, the following book can be a great choice. molecular and cellular mechanisms of neuronal plasticity in normal aging and alzheimers di...
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Morphometric studies of the tail of the caudate nucleus, the site where the pathology is first seen, were performed on 16 brain specimens collected from individuals at risk for inheriting Huntington's disease (HD). Medical records and information obtained from immediate family members indicated that all had died without symptoms of HD. Six individuals had 37 or more CAG repeats and were designa...
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ژورنال
عنوان ژورنال: Folia Neuropathologica
سال: 2013
ISSN: 1641-4640
DOI: 10.5114/fn.2013.34190